In the year 2040, Reito is put into cryostasis to wait for a cure for a rare disease. When he awakens five years later, the social order has collapsed:

– Reito investigates the MK virus's origin by visiting the widow of its first victim, discovering that those who dig too deep often disappear.

– The mystery deepens as Reito finds clues suggesting the virus may not have been a natural occurrence, while Shouta continues to spiral into his new life. Why the Series is Controversial

While other survivors like Kyoji Hino and Shouta Satou embrace their new status, Reito refuses to "mate," choosing instead to remain faithful to his missing childhood friend, Erisa Tachibana, and search for a true cure. Breakdown of Episodes 1–6

World's End Harem gained significant notoriety for its explicit content and production issues:

– Focuses on Shouta's psychological transformation as he adapts to life as the most "precious resource" in his school.

– Reito awakens to his new reality and meets his handler, Mira Suou, who pressures him to begin repopulation.